Disney?s upcoming animated feature Frozen just landed an additional director.? The Mouse House announced today that Jennifer Lee will be joining Chris Buck (Tarzan)as co-director on the princess movie.? Kristen Bell?voices a young dreamer named Anna who teams up with ?a daring mountain man? to find the Snow Queen (Idina Menzel) and put an end to a spell that has trapped their kingdom in eternal winter.? The film harkens back to some of Disney?s earlier, more music-centered films as it will feature original songs from Robert Lopez (The Book of Mormon) and Kristen Anderson-Lopez (In Transit).
Lee has already contributed to the screenplay for Frozen, so it appears she?s been involved with the project for a while.? She most recently was credited as one of the screenwriters for Disney?s Wreck-It Ralph, so hopefully she can bring some of the humor and heart of that film over to Frozen.? Hit the jump to read the press release.? The film opens in 3D on November 27, 2013.
Here?s the press release:
BURBANK, Calif. (November 29, 2012)?? Walt Disney Animation Studios (WDAS) taps Jennifer Lee to join Chris Buck at the helm of its 53rd?full-length animated feature ?Frozen,? which is slated for the big screen on Nov. 27, 2013. Lee, who has contributed to the film?s screenplay, is one of the screenplay writers of this year?s hit arcade-hopping adventure ?Wreck-It Ralph.?
Featuring the voices of Kristen Bell and Idina Menzel,??Frozen? is the coolest comedy-adventure ever to hit the big screen. When a prophecy traps a kingdom in eternal winter, Anna,?a fearless optimist, teams up with extreme mountain man Kristoff and his sidekick reindeer Sven on?an epic journey?to find Anna?s sister Elsa, the Snow Queen, and put an end to her icy spell. Encountering mystical trolls, a funny snowman named Olaf, Everest-like extremes and magic at every turn, Anna and Kristoff battle the elements in a race to save the kingdom from destruction.
?Frozen? producer Peter Del Vecho says the match-up is perfect. ?Jenn has a real connection to the film and creates dynamic and relatable characters. Her sense of comedy, adventure and story structure paired with Chris Buck?s vast experience and incredible instincts create an ideal situation for this film.?
Lee?s screen adaptation of John Steinbeck?s ?The Acts of King Arthur and His Noble Knights? is being produced by Troika Pictures. She has an original screenplay in development with Leonardo DiCaprio?s Appian Way, and her original script ?Lucid Dreams? was optioned by Wolfgang Peterson?s Radiant Productions. Lee holds an MFA in Film from Columbia University and a BA in English from the University of New Hampshire.
Buck directed (with Kevin Lima) Disney?s 1999 high-swinging feature ?Tarzan,? which won an Oscar? and a Golden Globe? for Best Music/Original Song (Phil Collins? ?You?ll Be in My Heart?). He directed (with Ash Brannon) 2007?s Oscar-nominated ?Surf?s Up? for Sony Pictures Animation.?His credits?within?animation also include 1989?s ?The Little Mermaid,? ?The Rescuers Down Under? (1990) and ?Pocahontas? (1995).
With original songs by Tony?-award winner Robert Lopez (?The Book of Mormon,? ?Avenue Q?) and Kristen Anderson-Lopez (?In Transit?),??Frozen??journeys into theaters Nov. 27, 2013, in Disney Digital 3D? in select theaters. For more information, like us on?Facebook:?http://www.facebook.com/DisneyFrozen.
MADISON, Wis. (AP) ? The Wisconsin Economic Development Corporation says Wisconsin is on pace to set a record for state exports this year.
Through the first three quarters of 2012, Wisconsin businesses exported $17.4 billion worth of products.
Lora Klenke, vice president of International Development with WEDC, says if exports continue to grow at this pace during the final quarter, they would total $23.5 billion. That would break last year's record of $22 billion.
Wisconsin exports during the first three quarters of 2012 grew faster than total U.S. exports. Wisconsin exported 6.4 percent more in the first three quarters of 2012 than in 2011, compared with 5 percent growth for the United States during the same period.
The top three markets for Wisconsin exports from January through September 2012 were Canada, Mexico and China.
NEW YORK (AP) ? Stocks are rising in early trading on Wall Street as optimism builds that a budget deal will be reached in Washington.
Later Thursday Treasury Secretary Timothy Geithner will meet with Senate Republican Leader Mitch McConnell and Senate Democratic Leader Harry Reid to push the negotiations forward.
The Dow Jones industrial average was up 50 points at 13,034 shortly after the opening bell.
The Standard & Poor's 500 index was up seven points at 1,416 and the Nasdaq composite rose 20 points to 3,012.
The Commerce Department raised its estimate for U.S. economic growth to an annual rate of 2.7 percent in the July-through-September period.
That's much better than the 2 percent rate estimated a month ago and more than twice the 1.3 percent rate logged in the April-June quarter.
Flipping through one of Psychology Today?s recent issues, my eyes focused on a short article ?Just Give In. Five Indulgences that actually boost self-control? by Kelly McGonigal, Ph.D.
What are these five indulgences? Personally, I was hoping chocolate was on the list. (Unfortunately, it?s not!) McGonigal narrows it down to these five things: a single espresso, an afternoon nap, a snack, YouTube and reality television.
The author writes that ?Willpower diminishes as the day wears on, but anything that reduces stress, boosts your mood, or recharges your energy can also reboot your self-control.?
Even ?reality TV??
Last night, after watching various contestants on a popular reality show sing for 90 minutes, I felt like falling asleep. Willpower? I must be watching the wrong program. Survivor might give me some energy: watching people trudge through swamps and sleep in tents, screaming at each other and falling in ?love? the next episode.
I kept reading, hopeful that the small paragraph devoted to the indulgence of reality television would explain our culture?s obsession with watching other people. People on a screen and not, say, upstairs in a different room or a phone call away.
?Willpower is contagious,? the author continues. ?Many reality shows feature people working hard to overcome obstacles as they lose weight, face their fears, or organize their clutter.?
I paused reading and recalled a past co-worker who spent, unfortunately, at least 30 minutes every single day talking about her favorite show, The Biggest Loser. We worked side-by-side and so this was particularly irritating, but even more so was the fact that she spent time talking to me ? and anyone else who would listen ? about her diets. She had a new diet every week and none of them worked.
I guess the show?s ?willpower? did not translate to her lifestyle. Sort of like how I can?t sing a note despite watching all of these silly singing shows.
The article concludes with ?You can ?catch? extra self-control just by watching someone pursue a goal.? Hmm. While the author of this article believes that television can boost willpower and productivity, I disagree. Watching television is a sedentary activity and it uses very few brain cells ? feeding your dog uses more. [Ed. - Although it may be a common popular perception, there's also little research that supports the idea that reality TV shows can help a person with their own willpower or act as a personal motivator.]
So, what?s the verdict? The reality is that watching reality television is a form of escape. I doubt it promotes ?self-control? (am I the only one who eats dinner while watching television?) but it has ingrained its way into our culture.
That aside, watching the presidential debates far exceeds the drama I have witnessed in any episode of Survivor. In the end, ?real life? is reality.
Reference
McGonigal, K. (2012, August). Just give in. Psychology Today, 45(4):13.
?
Woman with remote photo available from Shutterstock
????Last reviewed: By John M. Grohol, Psy.D. on 27 Nov 2012 ????Published on PsychCentral.com. All rights reserved.
APA Reference Champagne, N. (2012). Can Reality TV Boost Self-Control?. Psych Central. Retrieved on November 28, 2012, from http://psychcentral.com/blog/archives/2012/11/27/can-reality-tv-boost-self-control/
Mel Braham, chairman of The Harley Medical Group. Recently, the registered company was put into administration. Photograph: Harley Medical Group/PA
Source: Guardian | David Leigh
The millionaire head of a controversial cosmetic surgery chain, the biggest in the UK, owned a secret offshore company linked to the clinic, it can be revealed.
Mel Braham's Harley Medical Group has attracted criticism for refusing free replacements to women during the PIP silicone breast implant scandal. The Guardian/International Consortium of Investigative Journalists (ICIJ) inquiry has now identified Braham, who has an address in London, as the man behind an anonymous offshore entity registered in the British Virgin Islands under the name The Memphis Company Ltd.
When asked about the tax advantages of having an offshore account, Braham at first denied any connection between his clinic and the British Virgin Islands entity. He wrote: "This Memphis company that you refer to, has not, nor ever has had, any connection with the Harley Medical Group. To the best of my knowledge it has never traded or had any business transaction with the Harley Medical Group."
However, when the Guardian provided detailed evidence that the Memphis Company was in fact administered from the London headquarters of his Harley Medical Group, at 11 Queen Anne Street near Oxford Circus, Braham did not respond with any further comment. He would not explain the role of the Memphis Company.
Braham's cosmetic surgery chain is easily Britain's biggest, with a turnover of around ?30m. Braham, who formerly ran a hair transplant clinic in New Zealand, and now lives in a luxury flat at Chelsea Harbour, is recorded as having made large sums out of the business. His UK-registered company, the Harley Medical Centre Ltd, paid him director's fees of more than ?500,000 in 2010 and 2011.
In addition, a cash dividend of more than ?1m was paid out to his interests in 2010, via an offshore nominee company in Guernsey.
According to the Washington-based ICIJ's research, the Harley Medical Group's then financial controller, Simon Brazier, dealt with The Memphis Company's routine affairs, but Braham signed some correspondence personally. After Brazier's return to New Zealand, his successor as financial controller at the Harley Medical Group, Toni Culverwell, took over the role in 2010. Braham also set up a sister BVI company with an "Irish Branch" called the Harley Medical Group (Ireland) Ltd, which is openly registered in Dublin.
Braham faced controversy when he insisted in January this year that the Harley clinics could not afford the surgery for free replacement of the silicone implants they had inserted into almost 14,000 British women. The French supplier of the cheap PIP implants, which contained industrial-grade silicone instead of the much dearer medical-grade gel and had proved prone to rupture, is in jail in France, awaiting trial.
Braham, who described himself as "the innocent party", was quoted as saying: "We don't have the number of surgeons, the hospitals and the anaesthetists and we don't have the financial capacity to do it for nothing."
"We do roughly 5,000 to 6,000 operations a year and are not capable of adding another 13,900 on top of that."
Braham demanded the NHS pay for the bulk of the costs.
Faced with a legal class action from a group of aggrieved women demanding compensation, it was disclosed this month that Braham has now put the Harley Medical Centre Ltd into administration, while reopening and carrying on operations under another name, Aesthetic and Cosmetic Surgery Ltd. A Harley spokesman was quoted as saying: "Legal claims against Harley Medical Centre will no longer be able to take place." He added: "We were ... faced with liabilities arising from a class action that we simply wouldn't have been able to survive."
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ScienceDaily (Nov. 27, 2012) ? A NASA study using TRMM satellite data revealed that the year 2010 was a particularly bad year for landslides around the world.
A recent NASA study published in the October issue of the Journal of Hydrometeorology compared satellite rain data from NASA's Tropical Rainfall Measurement Mission (TRMM) to landslides in central eastern China, Central America and the Himalayan Arc, three regions with diverse climates and topography where rainfall-triggered landslides are frequent and destructive hazards to the local populations.
The work, led by Dalia Kirschbaum, a research physical scientist in the Hydrological Sciences Laboratory at NASA's Goddard Space Flight Center in Greenbelt, Md., is part of an ongoing effort to catalog worldwide rainfall-triggered landslides -- one of the world's lesser known but often catastrophic natural hazards. Locating them is a step in an effort to be able, one day, to predict and warn.
Currently, Kirschbaum explains, no consistent regional or global scale warning system exists for landslide disasters. To create one, scientists need to understand more than the individual factors that may contribute to local landslides -- the intensity and total amount of rainfall over hours to days, slope angle, soil type and saturation, among others.
"For other hazards like hurricanes, there's a clearly defined season," says Kirschbaum. "From satellite data and observations we know that hurricane season in the Atlantic spans from June 1 to Nov. 30. But we don't have that type of record for landslides around the world, and we want to know when and where to expect them in different regions."
Scientists also need a systematic way to assess landslide hazards for a region, and one way to do that, says Kirschbaum, is to look at the distribution and intensity of rain from satellite data and see how that correlates with where and how often landslides are being reported.
Creating Science by the Slice (of News)
The first step to developing landslide hazard assessments is to improve record keeping, Kirschbaum says. For the past several years, she has been developing the first global database for landslides triggered by rain, called the Global Landslide Catalog (GLC). Landslides are often too small to pick out of satellite imagery, so news stories are currently the best sources of information.
Daily, she and other research assistants examined media reports for possible landslides and dug out details such as where the landslide occurred, whether the landslide was triggered by a rain shower or a tropical cyclone, if there were fatalities, and if the type of landslide was characterized as a mudslide or a debris flow, among other characteristics. The GLC now has six complete years of data -- 2003, and 2007 through 2011 -- with new entries continually added. It contains more than 4,000 events that describe 20,600 reported fatalities among 60 different countries for 2007 through 2011.
However, Kirschbaum notes, landslide events are not uniformly reported around the world, with some not making the news unless they cause deaths or property damage. After compiling the 2010 record, Kirschbaum noted that 2010 appeared to be a particularly devastating year for landslides in parts of China, Central America and the Himalayan Arc. Kirschbaum compared the GLC with satellite-based rainfall information from TRMM and other satellites to see if the higher numbers of landslide reports corresponded with a higher amount of rainfall for those areas.
Fact-Checking the Stories with Impartial Witnesses
The TRMM Multisatellite Precipitation Analysis (TMPA) data includes rain data from 50 degrees north latitude to 50 degrees south latitude -- from southern Canada to the tip of South America--providing three-hourly and daily coverage of precipitation. Kirschbaum and her team relied on TMPA's 14-year record to provide a picture of global rainfall that could be related to landslides that occurred.
The big advantage of TMPA data, compared to ground data such as that from rain gauges, is that it measures rainfall in the same, consistent way over large regions. This provides a broader perspective that helps researchers like Kirschbaum and eventually forecasters equipped with satellite rainfall data to detect the kinds of rainfall signatures that are likely to produce destructive landslides.
Stating that extreme or prolonged rainfall can lead to landslides is not anything new, Kirschbaum says, but what is novel is that by examining the Global Landslide Catalog and TMPA precipitation record together, she can look at how reported landslide events compare with rainfall amounts. This in turn helps her find areas where landslides may be occurring but are not being reported.
Revealing the Long, Data-Drawn Truth
2010 was indeed an extraordinary year for landslides, says Kirschbaum, with three times as many reported events and twice as many reported fatal events as previous years within the Global Landslide Catalog.
Zhouqu County, China, was hit by the deadliest landslides in decades, according to state media, which buried some areas under as much as 23 feet (7 meters) of suffocating sludge. 1,765 people died. Property damages totaled an estimated $759 million. The TMPA rain data showed that the region's susceptible, steeply sloped geography was pummeled by extreme rainfall from a local cloudburst.
"This is really the first time that you can see how rainfall varies with respect to rainfall-triggered landslides because no other database has this type of globally consistent view," says Kirschbaum.
While most of the intense rainfall that triggers landslides is local in scale, global atmospheric circulation patterns can often affect these local conditions. As Kirschbaum explains: "What I think is unique about 2010 is there is a really strong El Ni?o going into a really strong La Ni?a, which consequently impacted rainfall patterns around the world."
Eventually, as the database of both landslides and rainfall data grows, Kirschbaum will be able to see more defined patterns in landslide occurrence month-by-month, and if those patterns are changing.
"I think in some ways we can compare the situation with landslides with that of earthquakes 50 years ago," says David Petley, professor and co-director of the Institute of Hazard, Risk and Resilience at Durham University's Department of Geography. "Our understanding of earthquakes improved dramatically when a global seismic array was deployed that allowed us to map earthquakes in space and time, providing insight into plate tectonics and thus earthquake mechanisms. We have not been able to map landslides in the same way, which means that we lack that time and space understanding. Dalia's work is important because she is collating this data, which is providing new insights."
Until there's enough data about where and when landslides have occurred in the past, there will not be enough information to issue useful warnings about future events at the global scale. Kirschbaum plans to expand the Global Landslide Catalog in order to provide a more complete dataset to evaluate landslide forecasting models. Adequate warning, one day, could help vulnerable people escape roaring slurries of slumping earth, to recover, rebuild or relocate.
This work was funded by the upcoming Global Precipitation Measurement (GPM) mission, which will improve upon current rainfall datasets, with real-time assessment of rainfall accumulations that lead to landslide triggering. The GPM Core satellite is set to launch in 2014 and will extend coverage of precipitation measurements using a constellation of satellites to deliver a global rain dataset every three hours.
For more information about the GPM mission, visit: http://www.nasa.gov/gpm
For more information about NASA's TRMM satellite, visit: http://trmm.gsfc.nasa.gov
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Story Source:
The above story is reprinted from materials provided by NASA/Goddard Space Flight Center.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
Dalia Kirschbaum, Robert Adler, David Adler, Christa Peters-Lidard, George Huffman. Global Distribution of Extreme Precipitation and High-Impact Landslides in 2010 Relative to Previous Years. Journal of Hydrometeorology, 2012; 13 (5): 1536 DOI: 10.1175/JHM-D-12-02.1
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
This photo combo provided by the Gagarin Cosmonaut Training Center via NASA, shows NASA astronaut Scott Kelly and Russian cosmonaut Mikhail Kornienko. Kelly and Kornienko will spend an entire year aboard the International Space Station beginning in 2015, according to reports, Monday, Nov. 26, 2012. The extended mission was approved almost two months ago to provide a medical foundation for future missions around the moon, as well as far-flung trips to asteroids and Mars. (AP Photo/Gagarin Cosmonaut Training Center via NASA)
This photo combo provided by the Gagarin Cosmonaut Training Center via NASA, shows NASA astronaut Scott Kelly and Russian cosmonaut Mikhail Kornienko. Kelly and Kornienko will spend an entire year aboard the International Space Station beginning in 2015, according to reports, Monday, Nov. 26, 2012. The extended mission was approved almost two months ago to provide a medical foundation for future missions around the moon, as well as far-flung trips to asteroids and Mars. (AP Photo/Gagarin Cosmonaut Training Center via NASA)
CAPE CANAVERAL, Fla. (AP) ? A former space shuttle commander whose twin brother is married to former Rep. Gabrielle Giffords will attempt the longest spaceflight ever by an American.
NASA astronaut Scott Kelly and Russian cosmonaut Mikhail Kornienko will spend an entire year aboard the International Space Station beginning in 2015.
Both countries' space agencies announced the names of the two veteran spacefliers on Monday. The extended mission was approved almost two months ago to provide a medical foundation for future missions around the moon, as well as far-flung trips to asteroids and Mars.
Both men already have lived aboard the space station for six months. NASA wanted experienced space station astronauts to streamline the amount of training necessary for a one-year stint. Officials had said the list of candidates was very short. They will begin training next year.
"Their skills and previous experience aboard the space station align with the mission's requirements," Bill Gerstenmaier, head of human exploration for NASA, said in a statement. "The one-year increment will expand the bounds of how we live and work in space and will increase our knowledge regarding the effects of microgravity on humans as we prepare for future missions beyond low-Earth orbit."
Kelly's identical twin brother, Mark Kelly, retired from the astronaut corps last year and moved to Tucson, Ariz., his wife's hometown. The former congresswoman was critically wounded in an assassination attempt in January 2011, while Scott Kelly was living aboard the space station.
NASA said neither crew member was available Monday to comment and that news conferences would be held next week to outline the mission.
Astronauts normally spend about four to six months aboard the space station. The longest an American lived there was seven months, several years back.
Russia, though, will continue to hold the world space endurance record.
Four cosmonauts spent at least a year aboard the old Mir space station. A Russian physician, Valery Polyakov, logged nearly 15 continuous months there in the mid-1990s.
Boris Morukov, head of the Moscow-based Institute for Medical and Biological Problems, Russia's main space medicine research center, told the Interfax news agency that communications and food rations for Kelly and Kornienko may be limited during their yearlong mission to better simulate interplanetary travel.
Kelly and Kornienko will launch aboard a Russian rocket from Kazakhstan. Americans must buy seats on Russian spacecraft now that NASA's shuttles have retired to museums, until private U.S. companies have vessels capable of carrying human passengers. That's still four or five years off.
Kelly is a 48-year-old, divorced Navy captain with two daughters. Kornienko, 52, a rocket engineer, is married with a daughter.
"We have chosen the most responsible, skilled and enthusiastic crew members to expand space exploration, and we have full confidence in them," Russian Space Agency chief Vladimir Popovkin said in the announcement.
___
AP writer Vladimir Isachenkov in Moscow contributed to this report.
The Wii U has only just arrived (with all of its streaming apps) and we're already discussing rumors for the next generation of Xbox. Meanwhile Comcast is letting users view TV on their mobile devices offline, and Verizon has launched live TV streaming to its iPad app. In sports news YouTube has locked up NBA D-League streaming, while ESPN continues to chase the bigger fish of the BCS Playoff games and the lure of TV money is helping shape conference expansion. We've also got news on a few new things to watch, so press play to listen in. We were having some RSS issues after the redesign, but those should be straightened out now -- if you still notice any problems let us know on Twitter or in the comments below.
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ScienceDaily (Nov. 26, 2012) ? This week a pioneering study published in the Proceedings of the National Academy of Sciences (PNAS) and co-authored by Dr. Alison Murray and Dr. Christian Fritsen of Nevada's Desert Research Institute (DRI) reveals, for the first time, a viable community of bacteria that survives and ekes out a living in a dark, salty and subfreezing environment beneath nearly 20 meters of ice in one of Antarctica's most isolated lakes.
Lake Vida, the largest of several unique lakes found in the McMurdo Dry Valleys, contains no oxygen, is mostly frozen and possesses the highest nitrous oxide levels of any natural water body on Earth. A briny liquid that is approximately six times saltier than seawater percolates throughout the icy environment that has an average temperature of minus 13.5 degrees centigrade (or 8 degrees Fahrenheit).
"This study provides a window into one of the most unique ecosystems on Earth," said Murray, the report's lead author, and molecular microbial ecologist and polar researcher for the past 17 years, who has participated in 14 expeditions to the Southern Ocean and Antarctic continent. "Our knowledge of geochemical and microbial processes in lightless icy environments, especially at subzero temperatures, has been mostly unknown up until now. This work expands our understanding of the types of life that can survive in these isolated, cryoecosystems and how different strategies may be used to exist in such challenging environments."
Despite the very cold, dark and isolated nature of the habitat, the report finds that the brine harbors a surprisingly diverse and abundant assemblage of bacteria that survive without a present-day source of energy from the sun. Previous studies of Lake Vida dating back to 1996 indicate that the brine and its' inhabitants have been isolated from outside influences for more than 3,000 years.
Murray and her co-authors and collaborators, including the project's principal investigator Dr. Peter Doran of the University of Illinois at Chicago, developed stringent protocols and specialized equipment for their 2005 and 2010 field campaigns to sample the lake brine while avoiding contaminating the pristine ecosystem.
To sample the unique environment researchers worked under secure, sterile tents on the lake's surface to keep the site and equipment clean as they drilled ice cores, collected samples of the salty brine residing in the lake ice and then assessed the chemical qualities of the water and its potential for harboring and sustaining life, in addition to describing the diversity of the organisms detected.
Geochemical analyses suggest that chemical reactions between the brine and the underlying iron-rich sediments generate nitrous oxide and molecular hydrogen. The latter, in part, may provide the energy needed to support the brine's diverse microbial life.
"It's plausible that a life-supporting energy source exists solely from the chemical reaction between anoxic salt water and the rock," explained Fritsen, a systems microbial ecologist and Research Professor in DRI's Division of Earth and Ecosystem Sciences.
"If that's the case," echoed Murray. "This gives us an entirely new framework for thinking of how life can be supported in cryoecosystems on earth and in other icy worlds of the universe."
Murray added further research is currently under way to analyze the abiotic, chemical interactions between the Lake Vida brine and the sediment, in addition to investigating the microbial community by using different genome sequencing approaches. The results could help explain the potential for life in other salty, cryogenic environments beyond Earth.
The Lake Vida brine also represents a cryoecosystem that is a suitable and accessible analog for the soils, sediments, wetlands, and lakes underlying the Antarctic ice sheet that other polar researchers are just now beginning to explore.
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The above story is reprinted from materials provided by Desert Research Institute.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
Alison E. Murray, Fabien Kenig, Christian H. Fritsen, Christopher P. McKay, Kaelin M. Cawley, Ross Edwards, Emanuele Kuhn, Diane M. McKnight, Nathaniel E. Ostrom, Vivian Peng, Adrian Ponce, John C. Priscu, Vladimir Samarkin, Ashley T. Townsend, Protima Wagh, Seth A. Young, Pung To Yung, and Peter T. Doran. Microbial life at ?13 ?C in the brine of an ice-sealed Antarctic lake. PNAS, November 26, 2012 DOI: 10.1073/pnas.1208607109
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
There are millions of different online businesses out there, and if you expect your particular business to be successful, then you need to implement some sound marketing techniques. By reading through this information, you will find valuable information on how to best utilize the Internet for marketing purposes. Keep reading for great Internet marketing information.
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Thomas Jefferson University honoring Axel Ullrich with Lennox K. Black International PrizePublic release date: 26-Nov-2012 [ | E-mail | Share ]
Contact: Steve Graff stephen.graff@jefferson.edu 215-955-5291 Thomas Jefferson University
2-day symposium Nov. 29-30 will focus on individualized medicine
PHILADELPHIAThomas Jefferson University will honor the renowned biotech researcher whose discoveries led to a slew of innovative drugs that revolutionized treatment including Herceptinone of the first gene-based medications for breast cancerwith its prestigious Lennox K. Black International Prize for Excellence in Biomedical Research.
Axel Ullrich, Ph.D., director of the Department of Molecular Biology at the Max Planck Institute of Biochemistry in Germany, will receive the recognition for his work in individualized medicine during a two-day symposium that will feature speakers from Jefferson, the National Institutes of Health (NIH), Johns Hopkins University, Genentech and former Kimmel Cancer Center at Jefferson Director Carlo Croce, M.D., Director of the Human Cancer Genetics Program at The Ohio State University.
The symposium, "Individualized Medicine," will be held November 29 and 30 on the Jefferson campus at the Dorrance H. Hamilton Building, Connelly Auditorium, 1001 Locust Street. The prize award and keynote speech by Dr. Ullrich will begin at 2:30 p.m. on Nov. 29. Michael J. Vergare, M.D., Senior Vice President of Academic Affairs, and Professor and Chair of the Department of Psychiatry at Jefferson, will present the award to Dr. Ullrich on behalf of the University.
The prize is awarded every two years to recognize the impact of pioneering biomedical research on the alleviation of human disease and suffering. Another goal is to draw the international scientific research community together in recognition of the ability of the spirit of human inquiry to transcend national boundaries and divisions.
For the past 25 plus years, Dr. Ullrich has been a leader in the biotechnology world, translating many of his basic science discoveries into clinical applications. Dr. Ullrich and his team's research led to the development of the drug Humulin (human insulin for diabetes), which is the first therapeutic agent ever to be developed through gene-based technology.
Another product based on Dr. Ullrich's work is the anti-cancer drug Herceptin (trastuzumab). In the mid-1980s, Dr. Ullrich and collaborators discovered that 30 percent of breast cancer patients overexpress the HER2 gene, which is a gene involved in the development of invasive cancers. This was the basis for the development of a monoclonal antibody that inhibits HER2 production, known as Herceptin, which been used since the late 1990s to treat patients with metastatic breast cancer. It has been shown to improve overall survival and prevents tumor recurrence in many women.
Dr. Ullrich received his primary degree in biochemistry at the University of Tubingen, Germany, and his Ph.D. from the University of Heidelberg in Molecular Genetics in 1975. He worked as a senior scientist at Genentech in San Francisco from 1978 to 1988. Since then, he has been Managing Director of the Max Plank Institute of Biochemistry.
He also received the 2010 Wolf Prize for research on human proto-oncogenes and development of novel cancer therapies.
After the award and keynote speech are delivered, Marc S. Williams, M.D., Director of the Genomic Medicine Institute, Geisinger Health System, and David Nash, M.D., MBA, Dean of Jefferson School of Population Health, will address the symposium. A poster session and reception hosted by the Chairman of the symposium planning committee, Stephen C. Peiper, M.D., Peter A. Herbut Professor and Chair, in the Department of Pathology, Anatomy and Cell Biology at Jefferson, will follow.
Several researchers will speak on Nov. 30, beginning at 8:30 a.m., at the Bluemle Life Sciences Building, 233 S 10th Street, Room 101, on "The Role of Structural Biology in Precision Medicine." That includes John M. Pascal, Ph.D., of the Department of Biochemistry and Molecular Biology at Jefferson, Wei Yang, Ph.D., a Senior Investigator and Section Chief at the National Institute of Diabetes and Digestive and Kidney Diseases at the NIH, Daniel J. Leahy, Ph.D., Professor of Biophysics and Biophysical Chemistry, Johns Hopkins University, and Chris Bowden, M.D., Vice President of Product Development for Signal Transduction Inhibitors, Genentech.
The full agenda can be found here: www.jefferson.edu/international_affairs/symposiums
The Lennox K. Black Prize is given biennially by Jefferson to an international researcher who is accomplished in his or her field. This year marks the 7th symposium for this award at Jefferson. Previous Lennox K. Black International Prize winners include Professor Harald zur Hausen, Ph.D., Nobel Laureate and Barry J. Marshall, AC, Nobel Laureate.
###
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Thomas Jefferson University honoring Axel Ullrich with Lennox K. Black International PrizePublic release date: 26-Nov-2012 [ | E-mail | Share ]
Contact: Steve Graff stephen.graff@jefferson.edu 215-955-5291 Thomas Jefferson University
2-day symposium Nov. 29-30 will focus on individualized medicine
PHILADELPHIAThomas Jefferson University will honor the renowned biotech researcher whose discoveries led to a slew of innovative drugs that revolutionized treatment including Herceptinone of the first gene-based medications for breast cancerwith its prestigious Lennox K. Black International Prize for Excellence in Biomedical Research.
Axel Ullrich, Ph.D., director of the Department of Molecular Biology at the Max Planck Institute of Biochemistry in Germany, will receive the recognition for his work in individualized medicine during a two-day symposium that will feature speakers from Jefferson, the National Institutes of Health (NIH), Johns Hopkins University, Genentech and former Kimmel Cancer Center at Jefferson Director Carlo Croce, M.D., Director of the Human Cancer Genetics Program at The Ohio State University.
The symposium, "Individualized Medicine," will be held November 29 and 30 on the Jefferson campus at the Dorrance H. Hamilton Building, Connelly Auditorium, 1001 Locust Street. The prize award and keynote speech by Dr. Ullrich will begin at 2:30 p.m. on Nov. 29. Michael J. Vergare, M.D., Senior Vice President of Academic Affairs, and Professor and Chair of the Department of Psychiatry at Jefferson, will present the award to Dr. Ullrich on behalf of the University.
The prize is awarded every two years to recognize the impact of pioneering biomedical research on the alleviation of human disease and suffering. Another goal is to draw the international scientific research community together in recognition of the ability of the spirit of human inquiry to transcend national boundaries and divisions.
For the past 25 plus years, Dr. Ullrich has been a leader in the biotechnology world, translating many of his basic science discoveries into clinical applications. Dr. Ullrich and his team's research led to the development of the drug Humulin (human insulin for diabetes), which is the first therapeutic agent ever to be developed through gene-based technology.
Another product based on Dr. Ullrich's work is the anti-cancer drug Herceptin (trastuzumab). In the mid-1980s, Dr. Ullrich and collaborators discovered that 30 percent of breast cancer patients overexpress the HER2 gene, which is a gene involved in the development of invasive cancers. This was the basis for the development of a monoclonal antibody that inhibits HER2 production, known as Herceptin, which been used since the late 1990s to treat patients with metastatic breast cancer. It has been shown to improve overall survival and prevents tumor recurrence in many women.
Dr. Ullrich received his primary degree in biochemistry at the University of Tubingen, Germany, and his Ph.D. from the University of Heidelberg in Molecular Genetics in 1975. He worked as a senior scientist at Genentech in San Francisco from 1978 to 1988. Since then, he has been Managing Director of the Max Plank Institute of Biochemistry.
He also received the 2010 Wolf Prize for research on human proto-oncogenes and development of novel cancer therapies.
After the award and keynote speech are delivered, Marc S. Williams, M.D., Director of the Genomic Medicine Institute, Geisinger Health System, and David Nash, M.D., MBA, Dean of Jefferson School of Population Health, will address the symposium. A poster session and reception hosted by the Chairman of the symposium planning committee, Stephen C. Peiper, M.D., Peter A. Herbut Professor and Chair, in the Department of Pathology, Anatomy and Cell Biology at Jefferson, will follow.
Several researchers will speak on Nov. 30, beginning at 8:30 a.m., at the Bluemle Life Sciences Building, 233 S 10th Street, Room 101, on "The Role of Structural Biology in Precision Medicine." That includes John M. Pascal, Ph.D., of the Department of Biochemistry and Molecular Biology at Jefferson, Wei Yang, Ph.D., a Senior Investigator and Section Chief at the National Institute of Diabetes and Digestive and Kidney Diseases at the NIH, Daniel J. Leahy, Ph.D., Professor of Biophysics and Biophysical Chemistry, Johns Hopkins University, and Chris Bowden, M.D., Vice President of Product Development for Signal Transduction Inhibitors, Genentech.
The full agenda can be found here: www.jefferson.edu/international_affairs/symposiums
The Lennox K. Black Prize is given biennially by Jefferson to an international researcher who is accomplished in his or her field. This year marks the 7th symposium for this award at Jefferson. Previous Lennox K. Black International Prize winners include Professor Harald zur Hausen, Ph.D., Nobel Laureate and Barry J. Marshall, AC, Nobel Laureate.
###
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Everytime I think the Democratic race card players could not get more vile, more deranged, more patronizingly demeaning to blacks, someone manages to defy even my vivid imagination.
This time, it is the Editorial Board of The Washington Post, which issued a truly amazing screed (h/t Gabriel Malor) claiming that critics of U.N. Ambassador Susan Rice are motivated by race and sex, as demonstrated by the facts that most are male and a significant percentage come from former confederate states (emphasis mine):
Could it be, as members of the Congressional Black Caucus are charging, that the [97 Republican House] signatories of the letter are targeting Ms. Rice because she is an African American woman? The signatories deny that, and we can?t know their hearts. What we do know is that more than 80 of the signatories are white males, and nearly half are from states of the former Confederacy. You?d think that before launching their broadside, members of Congress would have taken care not to propagate any falsehoods of their own.
The WaPo Editorial Board must have forgotten the opposition to Condoleezza Rice?s confirmation, which was led by former Klansman Robert Byrd and a guy who left a girl to die:
Leading the charge against Rice on Tuesday were Democratic Sens. Edward Kennedy of Massachusetts, Robert Byrd of West Virginia and Barbara Boxer of California.
Boxer, one of two Democrats to vote against Rice?s nomination in the Senate Foreign Relations Committee, said Rice?s answers to her questions were ?completely nonresponsive? and raised more issues about her credibility than they answered.
Rice, Condoleezza, received fewer favorable votes in her Secretary of State confirmation than any nominee in almost 25 years and more negative votes than any nominee in 180 years.? Twelve of the thirteen votes against Rice were from White Males, including the aforementioned former Klansman.
Boxer accused Rice of lying about Sadaam Hussein?s WMD program, and Rice pushed back that they relied on the available intelligence, among other things.
This would become a theme in Boxer?s continuously demeaning conduct towards Rice, which included mocking the fact that Rice had no children during the Iraq Surge hearings in January 2007 (note, Boxer also used the term ?dark cloud? which, had it been used by a Republican as to a black Democratic nominee, surely would have been called a dog whistle or worse)(full video here):
Boxer?s mocking of Rice, Condoleezza?s family status created a firestorm?of controversy, but plenty of liberals defended the attack.
Rice, Condoleeza, also was physically attacked at the start of those hearings, by White Liberals:
The Democrats? often personal attacks on Rice, Condoleezza, continued unabated (Kerry Picket has more).? Liberal cartoonists at major publications played on crude racial stereotypes in going after Rice, Condoleezza.
You get the point.
The criticisms of Rice, Condoleezza, on policy grounds were within the legitimate political realm, as are the criticisms of Rice, Susan.
In the criticisms of Rice, Susan, we have not seen from Republicans anything approaching the vitriol and crude racial and sexist comments directed at Rice, Condoleezza.
Does the?Editorial Board of The Washington Post even belief what it writes?? I doubt it.? It?s all part of their race card game.
Both men and women cheat ? regardless of race, age or stature, according to Terri Orbuch, author of Finding Love Again: 6 Simple Steps to a New and Happy Relationship. In fact, about 32 percent of married men and 20 percent of married women report being unfaithful, she said.
But when powerful men ? most recently CIA Director General David Petraeus ? admit to infidelity, we?re often taken aback. (Or maybe some of us aren?t that shocked, after all.)
Petraeus joins a long line of philanderers in prominent positions: Anthony Weiner, Eliot Spitzer, Bill Clinton and John Edwards, just to name a few.
But regardless of whether you?re surprised to hear these men strayed, the question is the same: Why?
Why do powerful men with such pivotal professions and important responsibilities commit adultery? Why do men with so much to lose ? great positions, families and reputations ? risk it all for a fling?
Power certainly may play a role. For instance, in a survey of 1,561 professionals, Joris Lammers, an assistant professor at Tilburg University, and colleagues found that the more power people had, the more likely they were to cheat. Plus, the more power people had, the more confident they were.
(They also found no gender differences in past cheating or the desire to cheat. Women were just as likely to cheat or want to cheat as men were.)
Initial research also points to fascinating brain findings when people are given just a fleeting sense of power. Lammers told NPR, ?You can see the brain structure associated with positive things, with rewards, is just much more activated than the part that is steered toward preventing the bad things from happening.?
The piece also talks about interesting research in college students, which found that when both male and female students were given a temporary sense of power, they tended to flirt more with a stranger of the opposite sex who sat next to them.
According to Orbuch, the sheer presence of temptation may explain why powerful men cheat. Power ? and all that comes with it, such as wealth and fame ? is attractive to many women, she said. And, sometimes, these women can become aggressive with their advances, she said.
Loneliness might be another reason. Men in power, including General Petraeus, are often away from their families for days, even weeks, Orbuch said. As a result, they end up yearning for female companionship, she said.
Some powerful men might crave the adrenaline rush. ?They perform well under high stress and continually need and enjoy excitement or challenges to drive them forward. An affair gives them that same type of exhilaration in their private life,? Orbuch said.
These individuals also are surrounded by yes-men who placate them ? and, often, their bad decisions. ?Powerful men tend to be surrounded by people who protect them, idolize them, and even ?enable? their vices in order to remain inside their influential orbit.?
Having people in your inner circle who constantly approve of your actions can swell your ego. And it can make you feel like the limits you once put on yourself are loosening ? and loosening, she said.
Powerful men might believe they?re impervious to getting caught or can conceal their transgressions because of the resources at their disposal, Orbuch said.
She also noted that powerful men ? and people in general ? cheat when they want change. ?Something in the man?s life or his relationship isn?t OK, and the affair creates the trigger for change,? she said. That something might be boredom after many years together, she said.
Powerful men may cheat for a variety of reasons. But the result is usually the same: Positions, reputations and families are irrevocably broken.
Why do you think powerful men cheat?
Margarita Tartakovsky, M.S. is an Associate Editor at Psych Central and blogs regularly about eating and self-image issues on her own blog, Weightless.
Like this author? Catch up on other posts by Margarita Tartakovsky, M.S. (or subscribe to their feed).
????Last reviewed: By John M. Grohol, Psy.D. on 24 Nov 2012 ????Published on PsychCentral.com. All rights reserved.
APA Reference Tartakovsky, M. (2012). Why Powerful Men Cheat. Psych Central. Retrieved on November 25, 2012, from http://psychcentral.com/blog/archives/2012/11/24/why-powerful-men-cheat/
DHAKA, Bangladesh - At least 112 people were killed in a fire that raced through a multi-story garment factory just outside of Bangladesh's capital, an official said Sunday.
The blaze broke out at the seven-story factory operated by Tazreen Fashions late Saturday. By Sunday morning, firefighters had recovered 100 bodies, fire department Operations Director Maj. Mohammad Mahbub told The Associated Press.
He said another 12 people who had suffered injuries after jumping from the building to escape the fire later died at hospitals. The death toll could rise as the search for victims was continuing, he said.
Local media reported that up to 124 people were killed in the fire. The cause of the blaze was not immediately clear, and authorities have ordered an investigation.
Bangladesh has some 4,000 garment factories, many without proper safety measures. The country annually earns about $20 billion from exports of garment products, mainly to the United States and Europe.
Relatives of the factory workers were frantically looking for their loved ones. Sabina Yasmine said she saw the body of her daughter-in-law, who died in the fire, but had no trace of her son, who also worked at the factory.
"Oh, Allah, where's my soul? Where's my son?" wailed Yasmine, who works at another factory in the area. "I want the factory owner to be hanged. For him, many have died, many have gone."
Mahbub said firefighters recovered 69 bodies from the second floor of the factory alone. He said most of the victims had been trapped inside the factory, located just outside of Dhaka, with no emergency exits leading outside the building.
Many workers who had taken shelter on the roof of the factory were rescued, but firefighters were unable to save those who were trapped inside, Mahbub said.
He said the fire broke out on the ground floor, which was used as a warehouse, and spread quickly to the upper floors.
"The factory had three staircases, and all of them were down through the ground floor," Mahbub said. "So the workers could not come out when the fire engulfed the building."
"Had there been at least one emergency exit through outside the factory, the casualties would have been much lower," he said.
Many of the victims were burned beyond recognition. The recovered bodies were kept in rows on the premise of a nearby school.
Army soldiers and paramilitary border guards were deployed to help police keep the situation under control as thousands of onlookers and anxious relatives of the factory workers gathered at the scene, Mahbub said. He would not say how many people were still missing.
Prime Minister Sheikh Hasina expressed shock at the loss of so many lives in the blaze and asked authorities to conduct thorough search-and-rescue operations.
The Bangladesh Garment Manufacturers and Exporters Association said it would stand by the victims' families.
Bangladesh's garment factories make clothes for brands including Wal-Mart, JC Penney, H&M, Marks & Spencer, Carrefour and Tesco.
Separately, a flyover under construction fell onto a busy market, leaving at least 14 people dead including three construction workers in southeastern city of Chittagong, an official said Sunday.
Local fire official Abdul Mannan said the concrete structure collapsed on Saturday night, and authorities recovered the bodies by Sunday morning from under the debris in the second-largest city after Dhaka.
You?ve eaten your turkey. You?ve lined up at large retailers to snag deals on big-ticket items. Or perhaps you relished in Black Friday at home, clicking away online from the comfort of your computer chair. But the chances to save during Thanksgiving weekend are not over. Small Business Saturday is here ? as is your chance to support black companies as this savings day builds its reputation.
Most people are familiar with Cyber Monday, which is coming up soon for eager online bargain hunters. But, the public is still warming up to Small Business Saturday. Tucked between two well-established savings frenzies, its appeal focuses on the more intimate nature of personal enterprises.
?Nestled between the often over-hyped Black Friday and Cyber Monday, Small Business Saturday is part of a burgeoning movement to support small, independent and local enterprises during the holiday season,? writes author Dan Danner of this phenomenon. ?Small Business Saturday is about Main Street, not Wall Street. It?s about the entrepreneurs, their employees, the families and communities they support. It?s about hard-working men and women who built their businesses from the ground up; who have put everything into the stores, factories and firms that offer what the chains and e-commerce companies cannot?something different, something personal, whether that be handcrafted gifts and other truly unique products, to genuinely friendly service.?
Lawrence Watkins, a frequent contributor to theGrio,?is also the?co-founder of?Ujamaa Deals, a?daily deals web destination that focuses on black-owned entities; thus, he has his ear to the streets regarding the best of black small business offerings. View his recommendations below for unique products and services that have that personal touch missing from large retailers, if you want to support both Small Business Saturday and African-American firms.
According to Watkins, promoting?black small businesses can ultimately give African-Americans the capital necessary to address our challenges.
?If there is one thing that the black community can do to increase our collective power, it is buying black,? Watkins, who is also the founder of?Great Black Speakers, told theGrio. ?Underdeveloped economics is currently the root cause of the many social issues that our neighborhoods face. The civil rights movement gave us political equality; now it is time for us to focus on economic equality.?
TheGrio?s Small Business Saturday Shopping Sampler
DN|Be Apparel? The funky gear available here stays true to the mission of the brand to, ?promote positive messages, knowledge, and intellectual curiosity to the youth through fashion, entertainment, and media in order to help combat the negative messages that they are bombarded with every day,? as?its site states.
Laguna Candles Candles always make a great gift. This site has a great selection, and also offers other scented products for bath and body.
Peppermint Chic Jewelry? Peppermint Chic offers affordable, cool accessories enabling gift-giving that helps you stay within your budget.
Puzzles For Us These crossword puzzles depicting black history will likely delight and inspire those gifted with them.
Cush Cosmetics Natural Hair and Skin Care All natural beauty products are all the rage, allowing one to look pretty without the chemicals found in most mainstream products.
Gwen?s Blends Skin Care These natural skin care products offer a fresh alternative to Carol?s Daughter, and another option for those on a quest to find natural blends with that perfect affinity for you.
Heaven Must Be Like This Pound Cakes These Avage-sweetened desserts offer a healthier alternative to traditional sweets.
The Kakakiki Brush/Comb for black hair This unique combs works to detangle the many different textures of African-American hair through its innovative design.
Will you be buying black for Small Business Saturday?
Follow Alexis Garrett Stodghill on Twitter at @lexisb
Although everyone has Black Friday on their minds, it's not too early to start thinking ahead about Cyber Monday. In fact, there are some online deals going on now. Check out what's in store for consumers this coming Monday:
Beauty
Beauty Bar: On Cyber Monday, spend $100 and get $20 off your purchase with the code BBCYBERMONDAY.
Bobbi Brown: On Nov. 26, you'll get five samples of your choice along with free shipping.
The Body Shop: On Nov. 23-26, the entire site is three for $30 (some exceptions apply).
Dr. Brandt: Save 50 percent on Dr. Brandt's full-sized eye creams (plus, snag free shipping) on Cyber Monday. In addition, from Nov. 27-Dec. 2, save 40 percent on select skin care classics on the site.
Fekkai: From Nov. 23-26, all orders will be 20 percent off with free shipping.
H2O Plus: Starting Nov. 23, H2O is offering its Blockbuster Bestsellers Bag (a $72 value) for only $27.
HauteLook: Nab a one-of-a-kind navy-and-white-striped cosmetic bag overflowing with beauty samples for $20 plus shipping starting Nov. 23. You'll also receive a $20 Sole Society gift card.
Hydroxatone: Receive 30 percent off any purchase of $150 and more on Nov. 26 using the code CYBER.
Lab Series: Stock up for your man on Nov. 26-30, when the entire site is 25 percent off.
Mineral Fusion: From Nov. 26 through the end of the month, you'll get 20 percent off the entire site, plus free shipping on orders of $50 or more.
Nars: On the 26th and 27th, the entire site is 20 percent off.
Philosophy: Score a deluxe gift, which includes a limited-edition tote and an assortment of bestselling Philosophy products, with purchase of $75 or more on Cyber Monday. Just use the code DELIGHT at checkout.
Shu Uemura: Nov. 22-27, get 20 percent off plus free shipping on all orders over $50. Use the code WISH2012 when you check out.
Smashbox: Friends and family get 20 percent off orders of $50 or more from Nov. 22-26. Use the code FRIENDS2012 at checkout.
Check out BellaSugar's full list for a more extensive array of Cyber Monday and Black Friday deals.
Fitness
Zobha: From Nov. 17-26, get $20 off $100 using the code ZBTHX20, $50 off $250 using the code ZBTHX50, or $100 off $500 using the code ZBTHX100.
Food
Wine.com: Until Nov. 30, save 5 percent on orders of 12 or more bottles using the code WINECASE5, or save 10 percent on all wine gift sets and gift baskets. Use code WINEGIFT10 in your cart.
Food Network Store: Until Dec. 27, get 15 percent off entire order with code C89452.
Tech
Case-Mate: From Nov. 23-26, get 20 percent off sitewide when you enter the code BLACKFRIDAY20.
Read on for more Cyber Monday sales.
Fashion
Shopbop: Nov. 20-26, you'll save 20 percent on purchases of $250 or more, 25 percent on purchases of $500 or more, 30 percent on orders over $1,000, and 35 percent on orders upward of $1,500 with code BIGEVENT12 at checkout.
Madewell:?Take advantage of the discounts right now with?25 percent off everything?online and in stores with code TREAT.
Alice + Olivia:?From Nov. 21-26, take 20 percent off?sitewide.
Diane von Furstenberg: Nov. 21-26, take?30 percent off?sale items with code HOLIDAYSALE ? plus free ground shipping.
Piperlime: From Nov. 23-26, receive 20 percent off?the site's wide range of fashions for the whole family.
Express:?Nov. 26, get 40 percent off everything plus free shipping?online.
Rory Beca:?Nov. 26, you'll get 30 percent off sitewide?plus free shipping.
J.Crew Factory: From Nov. 21-26, take?40 percent off?everything: jackets, sweaters, shoes, jewelry ? it doesn't get better than that, people.
French Connection:?From Nov. 21-26, receive free shipping, plus 30 percent off all orders of $150 or more.
Mackage:?From Nov. 23-26,?save up to 50 percent?on the brand's sleek designs online and in stores.
AllSaints: From Nov. 22-26, get your cool-girl fix with?20 percent off sitewide: coated jeans, chic knits ? you name it.
Ted Baker London:?Enjoy 30 percent off a range of the brands' polished wares?from Nov. 23-26.
Karmaloop:?Get your on-trend fix with 20 percent off orders $75 or more; enter code POPSUGAR ? valid Nov. 26-Dec. 31.
Vince Camuto:?From Nov. 23-27, find your perfect pair of shoes and take 30 percent off sitewide with special code HOLIDAY.
Revolve:?All Thanksgiving weekend long, enjoy sale items marked up to a whopping 95 percent off, plus free shipping.
For a full list of incredible Black Friday and Cyber Monday clothing deals, head over to FabSugar.
Home
Casa.com: You'll get 20-50 percent off a variety of home accents from popular brands like Jonathan Adler and DwellStudio. Ends Nov. 26.
Waterworks: On Nov. 26, shop the site's gorgeous luxury bath products, and you'll get 25 percent off your entire order, plus free standard shipping.
Horne: On Nov. 26, check out the curated picks in this online boutique, and with the code MONDAY15, you'll get 15 percent off most items with a few brand exceptions.
Coyuchi: The bedding and clothing company is offering 20 percent off its selection of cozy robes and sleepwear from Nov. 23-26.
Crane & Canopy: On Nov. 26, shop luxurious modern bedding with classic, beautiful prints, and receive 20 percent off your purchase.
Harabu House: Check out the site's cool, exotic home goods, and get 20 percent off your entire order using the code BFCM20OFF from Nov. 23-26.
DwellStudio: Get free ground shipping with code GOBBLE201 on Nov. 26.
For more home deals, check out CasaSugar's full list.
Baby
BabyLegs: Three pairs for $12. Coupon code available on website at 12:01 a.m. on Nov. 23. Sale valid Black Friday through Cyber Monday.
Zutano: 25 percent off entire site. "Like" Zutano on Facebook or sign up for the Zutano newsletter to receive the secret code. Valid on Cyber Monday only.
Seedling Kids: 25 percent off entire website on Cyber Monday with promo code Gobble.
Baby Wit: 30 percent off entire site with promo code BLACKFRIDAY2012. Valid Black Friday through Cyber Monday.
Motherhood Maternity: In-store and online, spend $75 or more, and receive a $50 Restaurant.com gift certificate. Valid Nov. 21 through Dec. 24.
Destination Maternity: In store and online, spend $125 or more, and receive a $75 Restaurant.com gift certificate. Valid Nov. 21 through Dec. 24.
Fawn Shoppe: 40 percent off entire store on Cyber Monday (use promo code CYBERSHOPPE at checkout).
FabKids: On Cyber Monday, new members get their first FabKids outfit for $25 (normally $40). Existing members receive a faux-fur jacket ($55 value) with the purchase of three outfits.
Plum District: 20 percent off sitewide sale on Cyber Monday; enter code CyberM20.
The Honest Company: On Cyber Monday, in addition to the Gift Bundle discounts, all orders will receive free shipping and a trio of organic lip balms.
Disney Publishing: On Nov. 26 only, Disney Publishing is offering significant discounts on some of its favorite kids' apps, including Cars 2 Read and Race, Tangled, and Brave Storybooks.
Serena & Lily: 25 percent off sitewide on Cyber Monday.
Children Inspire Design: 30 percent off entire site, plus free shipping on orders of $75 or more. Also offering a special holiday print and banner digital download to all orders placed on Black Friday or Cyber Monday. Use promo code CIDHOLIDAY12.
Wall Stories: 20-percent discount on all wall decals with promo code KIDFRIENDLY. Valid Black Friday and Cyber Monday.
Rosenberry Rooms: 20 percent off selected gift items; prices will be marked down on site. Valid Black Friday through Cyber Monday.
Olli & Lime: 30 percent off with promo code THANKS12. Excludes wall graphics, mobiles, and Jellycat products. Valid Nov. 22-27.
For more baby and maternity Black Friday and Cyber Monday deals, check out the full LilSugar list here.